![[6]Gingerol Ameliorates CisplatinInduced Pica by Regulating the TPH .](/2k17wtj/532.jpg)
[6]Gingerol Ameliorates CisplatinInduced Pica by Regulating the TPH .
· TPH, MAOA, SERT, and 5HT 3 receptor are important in 5HT metabolism, and cisplatininduced alterations in the associated protein/mRNA levels were restored when treated with [6]gingerol. Conclusion: This suggests that the antiemetic effect of [6]gingerol against cisplatininduced emesis may be due to 5HT attenuation via modulating the TPH/MAO .